Barriers to Linkage to Care for Hepatitis B Virus Infection: A Qualitative Analysis in Burkina Faso, West Africa

Tamara Giles-Vernick (1) , Fabienne Hejoaka (2, 3) , Armande Sanou (4) , Yusuke Shimakawa (1) , Issiaka Bamba (5) , Abdoulaye Traore (4)

1 Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology
2 TransVIHMI - Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes
3 Crem - Centre de Recherche sur les Médiations
4 GRAS - Groupe de recherche action en santé
5 Centre Muraz [Bobo-Dioulasso, Burkina Faso]

Hepatitis B virus (HBV) infection is a critical global health problem. The World Health Organization (WHO) has recently developed a global elimination strategy for HBV infection. Increasing access to screening, liver assessment, and antiviral treatment are crucial steps in achieving this goal. Little is known, however, about obstacles to linkage to care in low-and middle-income countries. Using a grounded theory approach, this qualitative study sought to characterize the diagnostic itineraries of people with chronic HBV infection in Burkina Faso, a west African country with high HBV prevalence, to identify barriers to linkage from screening to specialist care with hepatic assessment (alanine transaminase and hepatitis B e antigen or HBV DNA). We conducted 80 semistructured interviews with chronically infected people, their families, medical personnel, and traditional practitioners, and participant observation of HBV diagnostic announcements and consultations. Of 30 individuals diagnosed with chronic viral hepatitis, 18 inadvertently discovered their status through blood screening and 12 actively sought diagnosis for their symptoms. Only a quarter (8/30) were linked to care. Barriers included: 1) patients' ability to pay for testing and treatment; 2) a formal health system lacking trained personnel, diagnostic infrastructures, and other resources; 3) patients' familial and social networks that discouraged access to testing and HBV knowledge; 4) a well-developed demand for and provisioning of traditional medicine for hepatitis; and 5) a weak global politics around HBV. More training for medical personnel would improve linkage to care in sub-Saharan Africa. Developing effective communications between medical workers and patients should be a major priority in this elimination strategy.

Domains: Santé publique et épidémiologie; Infectious diseases; Social Anthropology and ethnology

Tamara Giles-Vernick, Fabienne Hejoaka, Armande Sanou, Yusuke Shimakawa, Issiaka Bamba, et al.. Barriers to Linkage to Care for Hepatitis B Virus Infection: A Qualitative Analysis in Burkina Faso, West Africa. American Journal of Tropical Medicine and Hygiene, 2016, 95, pp.1368 - 1375. ⟨10.4269/ajtmh.16-0398⟩. ⟨pasteur-02548814⟩