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Journal articles
Gag p27-Specific B- and T-Cell Responses in Simian Immunodeficiency Virus SIVagm-Infected African Green Monkeys
Abstract : Nonpathogenic simian immunodeficiency virus SIVagm infection of African green monkeys (AGMs) is characterized by the absence of a robust antibody response against Gag p27. To determine if this is accompanied by a selective loss of T-cell responses to Gag p27, we studied CD4 and CD8 T-cell responses against Gag p27 and other SIVagm antigens in the peripheral blood and lymph nodes of acutely and chronically infected AGMs. Our data show that AGMs can mount a T-cell response against Gag p27, indicating that the absence of anti-p27 antibodies is not due to the absence of Gag p27-specific T cells.
Cited literature [27 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-01969024
Contributor : Brigitte Bidault <>
Submitted on : Thursday, January 3, 2019 - 3:45:01 PM
Last modification on : Monday, June 15, 2020 - 12:02:03 PM
Long-term archiving on: : Thursday, April 4, 2019 - 2:49:03 PM
Contributor : Brigitte Bidault <>
Submitted on : Thursday, January 3, 2019 - 3:45:01 PM
Last modification on : Monday, June 15, 2020 - 12:02:03 PM
Long-term archiving on: : Thursday, April 4, 2019 - 2:49:03 PM
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