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Pertussis in Argentina and France.

Valérie Caro 1 Valérie Bouchez 1 Nicole Guiso 1 Blanca Gatti 2 Maria Rosa Agosti 3 Silvia E Gonzàlez Ayala 3
1 CNR - Prévention et thérapie moléculaires des maladies humaines. Centre National de Référence de la Coqueluche et autres bordetelloses
2 Laboratorio de Microbiología
3 Servicio Enfermedades Infecciosas
Abstract : We have studied the epidemiology of pertussis in two countries, Argentina and France, which have similar histories of long-term mass vaccination with a whole-cell vaccine. Both countries display a comparable epidemiology, with an increase of the incidence of the disease in non-vaccinated newborns. We used pulsed-field gel electrophoresis (PFGE) analysis and genotyping to compare Bordetella pertussis clinical isolates recovered in Argentina and France in 2001-2004. The majority of the isolates harbors prn2 allele and belongs to PFGE IVbeta group. Isolates were found to be very similar genetically suggesting a common evolution of the disease in these two countries using the same vaccine.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-00169332
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Submitted on : Monday, September 3, 2007 - 2:03:52 PM
Last modification on : Monday, January 13, 2020 - 5:08:06 PM

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Valérie Caro, Valérie Bouchez, Nicole Guiso, Blanca Gatti, Maria Rosa Agosti, et al.. Pertussis in Argentina and France.. Vaccine, Elsevier, 2007, 25 (22), pp.4335-9. ⟨10.1016/j.vaccine.2006.08.024⟩. ⟨pasteur-00169332⟩

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