Detecting Cellular Senescence in Reprogramming

Coralie Cazin (1) , Mathieu von Joest (1) , Han Li (1)

1 Plasticité cellulaire et Modélisation des Maladies / Cellular Plasticity and Disease Modelling

Cellular senescence has been suggested to facilitate tissue regeneration via promoting cellular plasticity. Here, we describe multiple systems, both in vitro and in vivo, to detect senescence in the context of cellular reprogramming.

Mots clés: Cellular senescence; Reprogramming; Cellular plasticity; SA-β-Gal

Domaines: Sciences du Vivant [q-bio]; Biologie cellulaire

Coralie Cazin, Mathieu von Joest, Han Li. Detecting Cellular Senescence in Reprogramming. Marco Demaria. Cellular Senescence: methods and protocols, 1896, Humana Press, pp.1-10, 2019, Methods in Molecular Biology, 978-1-4939-8931-7 (ebook). ⟨10.1007/978-1-4939-8931-7_1⟩. ⟨hal-03525632⟩