Skip to Main content Skip to Navigation
Journal articles

Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character

Nicolas Cabanel 1 Isabelle Rosinski-Chupin 1 Adriana Chiarelli 1, 2 Tatiana Botin 1 Marta Tato 3 Rafael Canton 3 Philippe Glaser 1
1 EERA - Ecologie et Evolution de la Résistance aux Antibiotiques / Ecology and Evolution of Antibiotics Resistance
2 USPC - Université Sorbonne Paris Cité
3 Hospital Universitario Ramón y Cajal [Madrid]
Abstract : Evolution of multidrug-resistant bacterial pathogens occurs at multiple scales, in the patient, locally in the hospital, or more globally. Some mutations or gene acquisitions, for instance in response to antibiotic treatment, may be restricted to a single patient due to their high fitness cost.
Keywords : Klebsiella pneumoniae carbapenemase drug resistance evolution insertion sequence mobile genetic elements urease
Document type :
Journal articles
Complete list of metadata
https://hal-pasteur.archives-ouvertes.fr/pasteur-03519675
Contributor : Reine Bouyssie Connect in order to contact the contributor
Submitted on : Monday, January 10, 2022 - 3:49:07 PM
Last modification on : Thursday, January 13, 2022 - 4:42:17 AM

File

Vignette du document
Cabanel-ASM-mSystems_2021pdf.p...
Publication funded by an institution

Licence

Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

PASTEUR | ANR | CNRS

Citation

Nicolas Cabanel, Isabelle Rosinski-Chupin, Adriana Chiarelli, Tatiana Botin, Marta Tato, et al.. Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character. mSystems, 2021, 6 (3), pp.e0024421. ⟨10.1128/mSystems.00244-21⟩. ⟨pasteur-03519675⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Les métriques sont temporairement indisponibles