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Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in Domestic Mice in Gabon: Risk of Emergence of LCMV Encephalitis in Central Africa

Abstract : ABSTRACT Lymphocytic choriomeningitis virus (LCMV) can cause acute fatal disease on all continents but was never detected in Africa. We report the first detection of LCMV RNA in a common European house mouse ( Mus musculus domesticus ) in Africa. Phylogenetic analyses show a close relationship with North American strains. These findings suggest that there is a risk of the appearance of LCMV acute encephalitis cases. This is a perfect example of virus dissemination by its natural host that may have dramatic public health consequences.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-03516026
Contributor : Nicolas BERTHET Connect in order to contact the contributor
Submitted on : Friday, January 7, 2022 - 6:03:11 AM
Last modification on : Friday, August 5, 2022 - 10:43:02 AM

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Nadine N′dilimabaka, Nicolas Berthet, Virginie Rougeron, Joa Braïthe Mangombi, Durand Patrick, et al.. Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in Domestic Mice in Gabon: Risk of Emergence of LCMV Encephalitis in Central Africa. Journal of Virology, 2015, 89 (2), pp.1456-1460. ⟨10.1128/JVI.01009-14⟩. ⟨pasteur-03516026⟩

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