A Nosocomial Outbreak of Human Monkeypox in the Central African Republic

Emmanuel Nakoune (1) , Emmanuel Lampaert (2) , Séverin Gervais Ndjapou , Carole Janssens (2) , Isabel Zuniga (2) , Michel van Herp (2) , Jean Paul Fongbia , Thomas Daquin Koyazegbe (3) , Benjamin Selekon (1) , Giscard Francis Komoyo (1) , Sandra Miriella Garba-Ouangole (1) , Casimir Manengu (3) , Jean-Claude Manuguerra (4) , Mirdad Kazanji (1) , Antoine Gessain (5) , Nicolas Berthet (4, 6)

1 Institut Pasteur de Bangui
2 Médecins Sans Frontières Belgique
3 OMS / WHO - Organisation Mondiale de la Santé / World Health Organization Office
4 ERI - Environnement et Risques infectieux - Environment and Infectious Risks
5 EPVO (UMR_3569 / U-Pasteur_3) - Epidémiologie et Physiopathologie des Virus Oncogènes / Oncogenic Virus Epidemiology and Pathophysiology
6 CIRMF - Centre International de Recherches Médicales de Franceville

Abstract An outbreak of familial monkeypox occurred in the Central African Republic in 2015/2016 by 3 transmission modes: familial, health care–related, and transport-related. Ten people (3 children and 7 adults) were infected. Most presented with cutaneous lesions and fever, and 2 children died. The viral strain responsible was a Zaire genotype strain.

Mots clés: Central African Republic; monkeypox; nosocomial outbreak

Domaines: Sciences du Vivant [q-bio]; Microbiologie et Parasitologie; Virologie

Emmanuel Nakoune, Emmanuel Lampaert, Séverin Gervais Ndjapou, Carole Janssens, Isabel Zuniga, et al.. A Nosocomial Outbreak of Human Monkeypox in the Central African Republic. Open Forum Infectious Diseases, 2017, 4 (4), pp.ofx168. ⟨10.1093/ofid/ofx168⟩. ⟨pasteur-03516016⟩