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Making Sense of the Biodiversity and Virulence of Listeria monocytogenes

Abstract : Manuscript Highlights  Listeria monocytogenes is a foodborne opportunistic bacterial pathogen  Classical genetic approaches in reference strains allowed identification of core virulence genes  Investigation of the species diversity of L. monocytogenes allowed uncovering hypoand hypervirulent strains and new virulence genes  Hypervirulent strains are host-associated, whereas hypovirulent strains are associated with food-processing environments  Accumulation of loss-of-function mutations in virulence pathways leads to niche restriction and obligate saprophytism
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Submitted on : Friday, June 25, 2021 - 4:07:34 PM
Last modification on : Saturday, July 24, 2021 - 3:15:10 AM


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Olivier Disson, Alexandra Moura, Marc Lecuit. Making Sense of the Biodiversity and Virulence of Listeria monocytogenes. Trends in Microbiology, Elsevier, 2021, ⟨10.1016/j.tim.2021.01.008⟩. ⟨pasteur-03271346⟩



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