Closed and high quality bacterial genomes of the Oligo Mouse Microbiota community

Quentin Lamy-Besnier (1, 2, 3) , Romain Koszul (2) , Laurent Debarbieux (1) , Martial Marbouty (2)

1 Bactériophage, bactérie, hôte - Bacteriophage, bacterium, host
2 Régulation spatiale des Génomes - Spatial Regulation of Genomes
3 UPD5 - Université Paris Descartes - Paris 5

The Oligo-Mouse-Microbiota (OMM 12) gnotobiotic murine model is an increasingly popular model for microbiota studies. However, following Illumina and PacBio sequencing, the genomes of the 12 strains could not be closed. Here, we used genomic chromosome conformation capture (Hi-C) data to reorganize, close and improve the quality of these 12 genomes.

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Life Sciences [q-bio]

Quentin Lamy-Besnier, Romain Koszul, Laurent Debarbieux, Martial Marbouty. Closed and high quality bacterial genomes of the Oligo Mouse Microbiota community. Microbiology Resource Announcements, 2021, 10 (17), pp.e01396-20. ⟨10.1128/MRA.01396-20⟩. ⟨pasteur-03204821⟩