Virus–Host Interactions in Archaea
Abstract
Viruses infecting archaea represent a unique part of the global virosphere with their virions and genomes typically showing no relationship to those of viruses infecting bacteria or eukaryotes. In this chapter, we summarize the state-of-the-art knowledge on various aspects of virus-host interactions in archaea, including (i) host recognition and entry, (ii) mechanisms of viral genome replication, (iii) transcriptional modulation of the viral and host genes during the course of the infection, (iv) mechanisms of virion egress, and (v) defense and viral counterdefense mechanisms in archaea.