Host specificity in the diversity and transfer of lsa resistance genes in group B Streptococcus

Pierre-Emmanuel Douarre (1) , Elisabeth Sauvage (1) , Claire Poyart (1, 2, 3) , Philippe Glaser (1)

1 Biologie des Bactéries pathogènes à Gram-positif - Biology of Gram-Positive Pathogens
2 Centre national de Référence des Streptocoques (CNR)
3 IC UM3 (UMR 8104 / U1016) - Institut Cochin

In group B Streptococcus (GBS), cross-resistance to lincosamides, streptogramin A and pleuromutilins (LSAP) is mediated by the acquisition of lsa genes. Here, we characterized the diversity, mobility and ecology of lsa genes in this species.

Domaines: Sciences du Vivant [q-bio]

Pierre-Emmanuel Douarre, Elisabeth Sauvage, Claire Poyart, Philippe Glaser. Host specificity in the diversity and transfer of lsa resistance genes in group B Streptococcus. Journal of Antimicrobial Chemotherapy, 2015, 70 (12), pp.3205-13. ⟨10.1093/jac/dkv277⟩. ⟨pasteur-03108155⟩