Skip to Main content Skip to Navigation
Journal articles

Molecular characterization of measles virus strains circulating in Cameroon during the 2013-2016 epidemics

Abstract : The first genotyping data on measles virus (MeV) strains in Cameroon dates from 1994, while other studies were realized in 2001 and 2011 with the establishment of MeV virological surveillance. However, the genetic data of MeV strains circulating in Cameroon remains fragmented and concentrated in certain regions, hence the need for an update. The objective of this study was to have recent data on MeV genotypes circulating in Cameroon. Ninety throat swabs collected during recent measles outbreaks were analyzed by MeV genotyping RT-PCR using the nucleoprotein gene N. The resulting sequences were analyzed on the basis of 450 nucleotides with MEGA 7 software. Overall genome analysis was performed on 40/90 sequences. The strains were from all ten regions and all belonged to cluster 1 of genotype B3. The genotype B3 has been circulating in Cameroon for long periods of time; efforts must be made in immunization for its elimination.
Document type :
Journal articles
Complete list of metadatas

Cited literature [26 references]  Display  Hide  Download

https://hal-pasteur.archives-ouvertes.fr/pasteur-02921762
Contributor : Charlotte Guy <>
Submitted on : Tuesday, August 25, 2020 - 2:52:16 PM
Last modification on : Friday, October 23, 2020 - 4:53:48 PM

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Collections

Citation

Franck-Martin Obam Mekanda, Chavely Gwladys Monamele, Frédy Brice Simo Nemg, Gilde Martial Yonga, Diane Ouapi, et al.. Molecular characterization of measles virus strains circulating in Cameroon during the 2013-2016 epidemics. PLoS ONE, Public Library of Science, 2019, 14 (9), pp.e0222428. ⟨10.1371/journal.pone.0222428⟩. ⟨pasteur-02921762⟩

Share

Metrics

Record views

58

Files downloads

66