P120catenin tuning of VE-cadherin endocytosis controls collective cell behavior during angiogenesis

Sandrine Etienne-Manneville (1)

1 Polarité cellulaire, Migration et Cancer - Cell Polarity, Migration and Cancer

How cells can stick together while moving through a complex environment is not fully understood. In this issue, Grimsley-Myers et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201909081) demonstrate that, in the case of blood vessel formation, the balance between the maintenance of endothelial integrity and the dynamics of cell-cell contacts required for collective migration relies on VE-cadherin endocytosis

Domaines: Santé publique et épidémiologie

Sandrine Etienne-Manneville. P120catenin tuning of VE-cadherin endocytosis controls collective cell behavior during angiogenesis. Journal of Cell Biology, 2020, 219 (5), pp.e202003005. ⟨10.1083/jcb.202003005⟩. ⟨pasteur-02918363⟩