Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel

Haidai Hu (1, 2) , Rebecca J. Howard (3) , Ugo Bastolla (4) , Erik Lindahl (3) , Marc Delarue (1)

1 Dynamique structurale des Macromolécules / Structural Dynamics of Macromolecules
2 ED515 - Ecole Doctorale Complexité du Vivant
3 Stockholm University
4 UAM - Universidad Autónoma de Madrid

Keywords: Ligand-gated ion channels; structural biology; crystallography; electrophysiology

Domains: Cristallography; Structural Biology [q-bio.BM]; Biochemistry, Molecular Biology; Bioinformatics [q-bio.QM]; Biological Physics [physics.bio-ph]; Cellular Biology

Haidai Hu, Rebecca J. Howard, Ugo Bastolla, Erik Lindahl, Marc Delarue. Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel. Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (24), pp.13437-13446. ⟨10.1073/pnas.1922701117⟩. ⟨pasteur-02905610⟩