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Intracellular offspring released from SFB filaments are flagellated

Abstract : The gut commensal segmented filamentous bacterium (SFB) attaches to the ileal epithelium and potently stimulates the host immune system. Using transmission electron microscopy (TEM), we show that mouse and rat SFB are flagellated above the concave tip at the unicellular intracellular offspring (IO) stage and that flagellation occurs prior to full IO differentiation and release of IOs from SFB filaments. This finding adds a missing link to the SFB life cycle.
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Contributor : Audrey Salles <>
Submitted on : Monday, June 15, 2020 - 11:19:33 PM
Last modification on : Wednesday, July 21, 2021 - 4:10:02 PM

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Iris Nkamba, Céline Mulet, Gyanendra Dubey, Olivier Gorgette, Aurélie Couesnon, et al.. Intracellular offspring released from SFB filaments are flagellated. Nature Microbiology, Nature Publishing Group, 2020, 5 (1), pp.34-39. ⟨10.1038/s41564-019-0608-1⟩. ⟨pasteur-02557372⟩



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