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Journal articles
Helicobacter bilis-Associated Suppurative Cholangitis in a Patient with X-Linked Agammaglobulinemia
Nicolas Degand
1
Justine Dautremer
2, 3
Benoit Pilmis
4
Agnès Ferroni
1
Fanny Lanternier
2, 3
Julie Bruneau
4
Olivier Hermine
5, 6
Stéphane Blanche
7
Xavier Nassif
1
Olivier Lortholary
2, 3
Marc Lecuit
6, 8, 2, 3
Fanny Lanternier 2, 3
Author
Julie Bruneau 4
Author
Olivier Hermine 5, 6
Author
Stéphane Blanche 7
Author
1
Laboratoire de Microbiologie [AP-HP Necker] (149 Rue de Sèvres, 75015 Paris - France)
- UPD5 - Université Paris Descartes - Paris 5 (12, rue de l'École de Médecine - 75270 Paris cedex 06 - France)
- CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
2
Service des Maladies infectieuses et tropicales [CHU Necker] (Paris 15 - France)
- CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
3
Centre d'infectiologie Necker-Pasteur [CHU Necker] (Service des Maladies infectieuses et Tropicales
Bâtiment Jean Hamburger
149 rue de Sèvres
75015 Paris - France)
- Institut Pasteur [Paris] (25-28, rue du docteur Roux, 75724 Paris cedex 15 - France)
- CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
4
Service d'AnatomoPathologie (Paris 75015 - France)
- AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) (France)
- UPD5 - Université Paris Descartes - Paris 5 (12, rue de l'École de Médecine - 75270 Paris cedex 06 - France)
- CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
5
Service d'Hématologie Adulte (161 Rue de Sèvres, 75743 Paris CEDEX 15 - France)
- AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) (France)
- CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
6
UPD5 - Université Paris Descartes - Paris 5 (12, rue de l'École de Médecine - 75270 Paris cedex 06 - France)
7
Service d'immuno-hématologie pédiatrique [CHU Necker] (149 Rue de Sèvres, 75015 Paris - France)
- AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) (France)
- CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
8
CHU Necker - Enfants Malades [AP-HP] (149 Rue de Sèvres 75015 Paris - France)
Abstract : Helicobacter bilis is a commensal bacterium causing chronic hepatitis and colitis in mice. In humans, enterohepatic Helicobacter spp. are associated with chronic hepatobiliary diseases.
Purpose : We aimed at understanding the microbial etiology in a patient with X-linked agammaglobulinemia presenting with suppurative cholangitis.
Methods : 16S rDNA PCR directly performed on a liver biopsy retrieved DNA of H. bilis.
Results : Clinical outcome resulted in the normalization of clinical and biological parameters under antibiotic treatment by a combination of ceftriaxone, metronidazole, and doxycyclin followed by a 2-week treatment with moxifloxacin and a 2-month treatment with azithromycin.
Conclusion : In conclusion, these data suggest a specific clinical and microbiological approach in patients with humoral deficiency in order to detect H. bilis hepatobiliary diseases.
Document type :
Journal articles
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Complete list of metadata
https://hal-pasteur.archives-ouvertes.fr/pasteur-02449154
Contributor : Andrée Diakite <>
Submitted on : Wednesday, January 22, 2020 - 4:44:41 PM
Last modification on : Friday, July 23, 2021 - 3:41:44 AM
Contributor : Andrée Diakite <>
Submitted on : Wednesday, January 22, 2020 - 4:44:41 PM
Last modification on : Friday, July 23, 2021 - 3:41:44 AM
Identifiers
- HAL Id : pasteur-02449154, version 1
- DOI : 10.1007/s10875-017-0437-z
- PUBMED : 28856582
Collections
PASTEUR | UNIV-PARIS5 | USPC | UNIV-PARIS
Citation
Nicolas Degand, Justine Dautremer, Benoit Pilmis, Agnès Ferroni, Fanny Lanternier, et al.. Helicobacter bilis-Associated Suppurative Cholangitis in a Patient with X-Linked Agammaglobulinemia. Journal of Clinical Immunology, Springer Verlag, 2017, 37 (7), pp.727-731. ⟨10.1007/s10875-017-0437-z⟩. ⟨pasteur-02449154⟩
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