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Decoding glycan recognition by bacterial toxins

Abstract : Functional and structural studies highlight the remarkable evolution and features of the typhoid toxin from Salmonella Typhi. This reveals that attachment of the toxin to specific N-glycan chains accounts for its tropism for selected human tissues.
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Submitted on : Wednesday, January 22, 2020 - 2:07:05 PM
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Sandrine Bourdoulous, Emmanuel Lemichez. Decoding glycan recognition by bacterial toxins. Nature Microbiology, 2018, 3 (2), pp.124-126. ⟨10.1038/s41564-018-0107-9⟩. ⟨pasteur-02448664⟩



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