Skip to Main content Skip to Navigation
Journal articles

A peridomestic Aedes malayensis population in Singapore can transmit yellow fever virus

Abstract : The case-fatality rate of yellow fever virus (YFV) is one of the highest among arthropod-borne viruses (arboviruses). Although historically, the Asia-Pacific region has remained free of YFV, the risk of introduction has never been higher due to the increasing influx of people from endemic regions and the recent outbreaks in Africa and South America. Singapore is a global hub for trade and tourism and therefore at high risk for YFV introduction. Effective control of the main domestic mosquito vector Aedes aegypti in Singapore has failed to prevent re-emergence of dengue, chikungunya and Zika viruses in the last two decades, raising suspicions that peridomestic mosquito species untargeted by domestic vector control measures may contribute to arbovirus transmission. Here, we provide empirical evidence that the peridomestic mosquito Aedes malayensis found in Singapore can transmit YFV. Our laboratory mosquito colony recently derived from wild Ae. malayensis in Singapore was experimentally competent for YFV to a similar level as Ae. aegypti controls. In addition, we captured Ae. malayensis females in one human-baited trap during three days of collection, providing preliminary evidence that host-vector contact may occur in field conditions. Finally, we detected Ae. malayensis eggs in traps deployed in high-rise building areas of Singapore. We conclude that Ae. malayensis is a competent vector of YFV and re-emphasize that vector control methods should be extended to target peridomestic vector species.
Document type :
Journal articles
Complete list of metadata

Cited literature [40 references]  Display  Hide  Download
Contributor : MARIE DEMESLAY GOUGAM Connect in order to contact the contributor
Submitted on : Tuesday, October 22, 2019 - 12:11:42 PM
Last modification on : Wednesday, September 28, 2022 - 8:30:25 AM
Long-term archiving on: : Thursday, January 23, 2020 - 5:19:48 PM


A peridomestic.pdf
Publication funded by an institution


Distributed under a Creative Commons Attribution 4.0 International License



Elliott F Miot, Fabien Aubry, Stéphanie Dabo, Ian H Mendenhall, Sébastien Marcombe, et al.. A peridomestic Aedes malayensis population in Singapore can transmit yellow fever virus. PLoS Neglected Tropical Diseases, Public Library of Science, 2019, 13 (10), pp.e0007783. ⟨10.1371/journal.pntd.0007783⟩. ⟨pasteur-02325668⟩



Record views


Files downloads