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Fatal Invasive Infection with Fungemia Due to Microascus cirrosus after Heart and Lung Transplantation in a Patient with Cystic Fibrosis

Abstract : Scopulariopsis species are rarely but increasingly recognized as opportunistic pathogens in immunocompromised patients. We report on a patient suffering from cystic fibrosis who developed disseminated fungal infection due to a rare Scopulariopsis species, Microascus cirrosus, after heart and lung transplantation. Despite antifungal combination therapy with voriconazole and caspofungin, the patient died 4 weeks after transplantation. Diagnostic difficulties and optimal management of disseminated Scopulariopsis/Microascus infections are discussed.
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Submitted on : Friday, August 2, 2019 - 3:29:29 PM
Last modification on : Monday, January 13, 2020 - 5:08:16 PM

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Charline Miossec, Florent Morio, Thierry Lepoivre, Patrice Le Pape, Dea Garcia-Hermoso, et al.. Fatal Invasive Infection with Fungemia Due to Microascus cirrosus after Heart and Lung Transplantation in a Patient with Cystic Fibrosis. Journal of Clinical Microbiology, American Society for Microbiology, 2011, 49 (7), pp.2743-2747. ⟨10.1128/JCM.00127-11⟩. ⟨pasteur-02262481⟩

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