Subcutaneous phaeohyphomycosis due to Phialemoniopsis ocularis successfully treated by voriconazole

Guillaume Desoubeaux (1, 2) , Dania García (3) , Eric Bailly (2) , Olivier Augereau (2) , Guillaume Bacle (2) , Anne de Muret (2) , Louis Bernard (1, 2) , José Cano-Lira (3) , Dea Garcia-Hermoso (4) , Jacques Chandenier (1, 2)

1 Université Francois Rabelais [Tours]
2 CHRU Tours - Centre Hospitalier Régional Universitaire de Tours
3 Universitat Rovira i Virgili
4 CNRMA - Centre National de Référence des Mycoses invasives et antifongiques - Mycologie moléculaire

We report a case of subcutaneous infection in a 67 year-old Cambodian man who presented with a 5-month history of swelling of the right foot. Histopathology was compatible with phaeohyphomycosis and the hyphomycete Phialemoniopsis ocularis was identified by the means of morphological and molecular techniques. The patient responded well to a 6-month oral treatment with voriconazole alone.

Keywords: Phaeohyphomycosis; Phialemoniopsis ocularis; Sarcopodium oculorum; Voriconazole

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Mycology

Guillaume Desoubeaux, Dania García, Eric Bailly, Olivier Augereau, Guillaume Bacle, et al.. Subcutaneous phaeohyphomycosis due to Phialemoniopsis ocularis successfully treated by voriconazole. Medical Mycology Case Reports, 2014, 5, pp.4-8. ⟨10.1016/j.mmcr.2014.04.001⟩. ⟨pasteur-02242791⟩