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Journal articles
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
Carolyne M Ndila
1
Sophie Uyoga
1
Alexander W Macharia
1
Gideon Nyutu
1
Norbert Peshu
1
John Ojal
1
Mohammed Shebe
1
Kennedy O Awuondo
1
Neema Mturi
1
Benjamin Tsofa
1
Nuno Sepúlveda
2
Taane G Clark
2
Gavin Band
1
Geraldine Clarke
1
Kate Rowlands
1
Christina Hubbart
1
Anna Jeffreys
1
Silvia Kariuki
3
Kevin Marsh
Margaret Mackinnon
Kathryn Maitland
Dominic P Kwiatkowski
4
Kirk A Rockett
1
Thomas N Williams
5
Malariagen Consortium
Kathryn Maitland
Author
Dominic P Kwiatkowski 4
Author
Kirk A Rockett 1
Author
Thomas N Williams 5
Author
Malariagen Consortium
Author
1
The Wellcome Trust Centre for Human Genetics [Oxford] (Roosevelt Drive, Oxford OX3 7BN, UK - United Kingdom)
- University of Oxford [Oxford] (Wellington Square, Oxford OX1 2JD - United Kingdom)
2
LSHTM - London School of Hygiene and Tropical Medicine (Keppel Street
London
WC1E 7HT
- United Kingdom)
3
The Wellcome Trust Sanger Institute [Cambridge] (Hinxton, Cambridge CB10 1SA, UK - United Kingdom)
4
University of Oxford [Oxford] (Wellington Square, Oxford OX1 2JD - United Kingdom)
5
St Mary's Hospital, Imperial College (United Kingdom)
- St Mary's Hospital, Imperial College (France)
Abstract : Background Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms-many related to the structure or function of red blood cells-and risk for severe Plasmodium falciparum malaria and its specific phenotypes, including cerebral malaria, severe malaria anaemia, and respiratory distress.
Document type :
Journal articles
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https://hal-pasteur.archives-ouvertes.fr/pasteur-02084676
Contributor : Anne Lassailly-Bondaz Connect in order to contact the contributor
Submitted on : Friday, March 29, 2019 - 4:44:03 PM
Last modification on : Saturday, March 30, 2019 - 1:37:31 AM
Long-term archiving on: : Sunday, June 30, 2019 - 3:40:00 PM
Contributor : Anne Lassailly-Bondaz Connect in order to contact the contributor
Submitted on : Friday, March 29, 2019 - 4:44:03 PM
Last modification on : Saturday, March 30, 2019 - 1:37:31 AM
Long-term archiving on: : Sunday, June 30, 2019 - 3:40:00 PM
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1-s2.0-S2352302618301078-main....
Publication funded by an institution
Licence
Distributed under a Creative Commons Attribution 4.0 International License
Identifiers
- HAL Id : pasteur-02084676, version 1
- PUBMED : 30033078
- DOI : 10.1016/S2352-3026(18)30107-8
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Citation
Carolyne M Ndila, Sophie Uyoga, Alexander W Macharia, Gideon Nyutu, Norbert Peshu, et al.. Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study. The Lancet Haematology, Elsevier, 2018, 5 (8), pp.e333-e345. ⟨10.1016/S2352-3026(18)30107-8⟩. ⟨pasteur-02084676⟩
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