Abstract : The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high.
https://hal-pasteur.archives-ouvertes.fr/pasteur-02060243
Contributor : Marie Martin <>
Submitted on : Thursday, March 7, 2019 - 11:51:05 AM Last modification on : Monday, January 13, 2020 - 5:08:17 PM Long-term archiving on: : Sunday, June 9, 2019 - 10:13:05 AM
Alain Agnememel, Eva Hong, Dario Giorgini, Viginia Nuñez-Samudio, Ala-Eddine Deghmane, et al.. Neisseria meningitidis Serogroup X in Sub-Saharan Africa.. Emerging Infectious Diseases, Centers for Disease Control and Prevention, 2016, 22 (4), pp.698-702. ⟨10.3201/eid2204.150653⟩. ⟨pasteur-02060243⟩