Neonatal Meningococcal Meningitis In France From 2001 To 2013.

Ali Bilal (1) , Muhamed-Kheir Taha (2) , Laurence Caeymaex (1, 3) , Robert Cohen (3, 4, 5, 6, 1) , Corinne Levy (4, 3, 6, 1) , Xavier Durrmeyer (1, 3, 6)

1 Service de Néonatologie [CHI Créteil]
2 CNR - Centre National de Référence des Méningocoques et Haemophilus influenzae - National Reference Center Meningococci and Haemophilus influenzae
3 CRC - Centre de Recherche Clinique [Créteil]
4 IMRB - Institut Mondor de Recherche Biomédicale
5 ACTIV - Association Clinique et Thérapeutique Infantile du Val de Marne
6 GPIP - Groupe de Pathologie Infectieuse Pédiatrique [Paris]

Among 831 cases of neonatal bacterial meningitis occurring from 2001 to 2013, Neisseria meningitidis was the third most frequent bacterial species found. All cases occurred only in term neonates and were mainly late onset. Serogroup B accounted for 78% of cases. At diagnosis, 27% of cases had at least one sign of disease severity. All strains were susceptible to cefotaxime, but 12% showed intermediate susceptibility to penicillin G and to aminopenicillin.

Keywords: Neisseria meningitidis; meningitis; neonate; mortality; earlyonset; late-onset

Domains: Life Sciences [q-bio]; Human health and pathology; Infectious diseases; Life Sciences [q-bio]; Microbiology and Parasitology; Bacteriology; Life Sciences [q-bio]; Santé publique et épidémiologie

Ali Bilal, Muhamed-Kheir Taha, Laurence Caeymaex, Robert Cohen, Corinne Levy, et al.. Neonatal Meningococcal Meningitis In France From 2001 To 2013.. Pediatric Infectious Disease Journal, 2016, 35 (11), pp.1270-1272. ⟨10.1097/INF.0000000000001296⟩. ⟨pasteur-02055841⟩