Archaeal tetrathionate hydrolase goes viral: secretion of a sulfur metabolism enzyme in the form of virus-like particles

Mart Krupovic (1) , Nuno Peixeiro (1) , Marcus Bettstetter , Reinhard Rachel (2) , David Prangishvili (1)

1 BMGE - Biologie Moléculaire du Gène chez les Extrêmophiles
2 UR - Universität Regensburg

In the course of screening for virus-host systems in extreme thermal environments, we have isolated a strain of the hyperthermophilic archaeaon Acidianus hospitalis producing unusual filamentous particles with a zipper-like appearance. The particles were shown to represent a secreted form of a genuine cellular enzyme, tetrathionate hydrolase, involved in sulfur metabolism.

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Microbiology and Parasitology; Virology

Mart Krupovic, Nuno Peixeiro, Marcus Bettstetter, Reinhard Rachel, David Prangishvili. Archaeal tetrathionate hydrolase goes viral: secretion of a sulfur metabolism enzyme in the form of virus-like particles. Applied and Environmental Microbiology, 2012, 78 (15), pp.5463-5465. ⟨10.1128/AEM.01186-12⟩. ⟨pasteur-01977406⟩