Skip to Main content Skip to Navigation
Journal articles

Acquisition of Beta-Lactamase by Neisseria meningitidis through Possible Horizontal Gene Transfer

Abstract : We report the detection in France of a beta-lactamase-producing invasive meningococcal isolate. Whole-genome sequencing of the isolate revealed a ROB-1-type beta-lactamase gene that is frequently encountered in Haemophilus influenzae, suggesting horizontal transfer between isolates of these bacterial species. Beta-lactamases are exceptional in meningococci, with no reports for more than 2 decades. This report is worrying, as the expansion of such isolates may jeopardize the effective treatment against invasive meningococcal disease.
Document type :
Journal articles
Complete list of metadatas

Cited literature [9 references]  Display  Hide  Download

https://hal-pasteur.archives-ouvertes.fr/pasteur-01950880
Contributor : Muhamed-Kheir Taha <>
Submitted on : Tuesday, December 11, 2018 - 10:22:04 AM
Last modification on : Monday, January 13, 2020 - 5:08:15 PM
Long-term archiving on: : Tuesday, March 12, 2019 - 1:48:24 PM

Identifiers

Collections

Citation

Eva Hong, Ala-Eddine Deghmane, Muhamed-Kheir Taha. Acquisition of Beta-Lactamase by Neisseria meningitidis through Possible Horizontal Gene Transfer. Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2018, 62 (9), pp.e00831-18. ⟨10.1128/AAC.00831-18⟩. ⟨pasteur-01950880⟩

Share

Metrics

Record views

142

Files downloads

372