Skip to Main content Skip to Navigation
New interface
Journal articles

Evidence of the presence of Seoul virus in Cambodia

Abstract : A study was conducted in agricultural and urban areas in Cambodia to assess the presence of hantaviruses in rodent populations. In 1998, rodents were trapped in two villages and in Phnom Penh city around market places and a rubbish dump. IgG antibodies to Hantaan virus were detected in 54 (8.2%) rodents among 660 tested: 6.4% (13/203) among roof rats (Rattus rattus), 20.9% (39/187) among Norway rats (R. norvegicus), 16.7% (2/12) among unidentified Rattus species and none in 183 Polynesian rats (R. exulans) or in 75 bandicoot rats (Bandicota sp.). The presence of the viral genome was detected by a reverse transcription-PCR amplifying part of the sequence coding for the nucleoprotein in the S segment, in 87% of the seropositive rodents. Thirty-one representative cDNAs were sequenced. Phylogenetic studies of the sequences indicated a close relationship with Seoul virus. However, the Cambodian Seoul virus sequences clustered within two different phylogenetic lineages, one associated with R. rattus and the other with R. norvegicus.
Complete list of metadata

Cited literature [14 references]  Display  Hide  Download
Contributor : Jean-Marc Reynes Connect in order to contact the contributor
Submitted on : Thursday, July 12, 2018 - 3:07:24 PM
Last modification on : Saturday, September 24, 2022 - 3:10:05 PM


2003-MI-SEOV KHM.pdf
Explicit agreement for this submission





Jean-Marc Reynes, Jean-Louis Soares, Thomas Hüe, Michele Bouloy, Sot Sun, et al.. Evidence of the presence of Seoul virus in Cambodia. Microbes and Infection, 2003, 5 (9), pp.769 - 773. ⟨10.1016/S1286-4579(03)00149-7⟩. ⟨pasteur-01836869⟩



Record views


Files downloads