Seroprevalence and Transmission of Human Influenza A(H5N1) Virus before and after Virus Reassortment, Cambodia, 2006–2014

Sowath Ly (1, 2) , Paul Horwood (1) , Malen Chan (1) , Sareth Rith (1) , Sopheak Sorn (1) , Kunthea Oeung (1) , Kunthy Nguon (1) , Siam Chan (1) , Phalla Y (1) , Amy Parry (3) , Reiko Tsuyuoka (3) , Sovann Ly (2) , Beat Richner (4) , Denis Laurent (4) , Sirenda Vong (1) , Philippe Dussart (1) , Philippe Buchy (1, 5) , Arnaud Tarantola (1)

1 Institut Pasteur du Cambodge
2 Ministry of Health [Phnom Penh]
3 WHO - World Health Organization [Phnom Penh]
4 Kantha Bopha Hospitals Foundation
5 GSK Vaccines R&D

Thirty-five human influenza A(H5N1) cases were reported in Cambodia during 2013-2014 after emergence of a clade 1.1.2 reassortant virus. We tested 881 villagers and found 2 cases of pauci- or asymptomatic infection. Seroprevalence after emergence of the reassortant strain (0.2%) was lower than the aggregate seroprevalence of 1.3% reported in earlier studies.

Keywords: Cambodia; H5N1 virus; avian influenza virus; highly pathogenic; humans; influenza; poultry; reassortment; seroepidemiologic study; seroprevalence; transmission; viruses

Domains: Life Sciences [q-bio]; Life Sciences [q-bio]; Human health and pathology; Infectious diseases; Life Sciences [q-bio]; Microbiology and Parasitology; Virology

Sowath Ly, Paul Horwood, Malen Chan, Sareth Rith, Sopheak Sorn, et al.. Seroprevalence and Transmission of Human Influenza A(H5N1) Virus before and after Virus Reassortment, Cambodia, 2006–2014. Emerging Infectious Diseases, 2017, 23 (2), pp.300 - 303. ⟨10.3201/eid2302.161232⟩. ⟨pasteur-01739351⟩