Aedes aegypti in Ho Chi Minh City (Viet Nam): susceptibility to dengue 2 virus and genetic differentiation

Tran Khanh Tien (1) , Marie Vazeille-Falcoz (2) , Laurence Mousson (2) , Tran Huu Hoang (1) , Francois Rodhain (2) , Nguyen Thi Huong (1) , Anna-Bella Failloux (2)

1 Institut Pasteur d'Ho Chi Minh Ville
2 Ecologie des Systèmes Vectoriels

Aedes aegypti is the principal vector of dengue viruses, responsible for a viral infection that has become a major public health concern in Asia. In Viet Nam, dengue haemorrhagic fever was first detected in the 1960s and is now a leading cause of death in childhood. We studied the variability in competence of Ae. aegypti as a vector for dengue 2 virus and genetic differentiation in this mosquito species. Twenty mosquito samples collected in 1998 in Ho Chi Minh City were subjected to oral infection and isoenzyme polymorphism analysis by starch gel electrophoresis. Ae. aegypti populations from the centre of Ho Chi Minh City were genetically differentiated and their infection rates differed from those of populations from the commuter belt. These results have implications for insecticidal control during dengue outbreaks.

Keywords: Aedes aegypti; dengue; oral susceptibility; population genetics; Viet Nam

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Virology

Tran Khanh Tien, Marie Vazeille-Falcoz, Laurence Mousson, Tran Huu Hoang, Francois Rodhain, et al.. Aedes aegypti in Ho Chi Minh City (Viet Nam): susceptibility to dengue 2 virus and genetic differentiation. Transactions of The Royal Society of Tropical Medicine and Hygiene, 1999, 93 (6), pp.581 - 586. ⟨10.1016/S0035-9203(99)90056-1⟩. ⟨pasteur-01715472⟩