Interaction of rabies virus P-protein with STAT proteins is critical to lethal rabies disease.

Résumé : Rabies virus (RABV) causes rabies disease resulting in >55,000 human deaths/year. The multifunctional RABV P-protein has essential roles in genome replication, and forms interactions with cellular STAT proteins that are thought to underlie viral antagonism of interferon-dependent immunity. However, the molecular details of P-protein-STAT interaction, and its importance to disease are unresolved.
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Journal of Infectious Diseases, Oxford University Press (OUP), 2014, 209 (11), pp.1744-53. 〈10.1093/infdis/jit829〉
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Contributeur : Anne Lassailly-Bondaz <>
Soumis le : mardi 28 février 2017 - 17:47:52
Dernière modification le : jeudi 11 janvier 2018 - 06:15:17

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Linda Wiltzer, Kazuma Okada, Satoko Yamaoka, Florence Larrous, Henna Veera Kuusisto, et al.. Interaction of rabies virus P-protein with STAT proteins is critical to lethal rabies disease.. Journal of Infectious Diseases, Oxford University Press (OUP), 2014, 209 (11), pp.1744-53. 〈10.1093/infdis/jit829〉. 〈pasteur-01479389〉

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