How cells kill a "killer" messenger

Cosmin Saveanu (1) , Alain Jacquier (1)

1 Génétique des Interactions macromoléculaires / Genetics of Macromolecular Interactions

Establishing a link between the nonsense-mediated decay pathway and a gene associated with programmed cell death could explain why this pathway is essential in most, but not all, eukaryotes.

Keywords: Upf2; cell biology; D. melanogaster; Drosophila; Gadd45; mRNA decay; NMD; Upf1

Domains: Life Sciences [q-bio]

Cosmin Saveanu, Alain Jacquier. How cells kill a "killer" messenger. eLife, 2016, 5, pp.e16076. ⟨10.7554/eLife.16076⟩. ⟨pasteur-01404013⟩