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Journal articles
Modeling the allosteric modulation of CCR5 function by Maraviroc
Abstract : Maraviroc is a non-peptidic, low molecular weight CC chemokine receptor 5 (CCR5) ligand that has recently been marketed for the treatment of HIV infected individuals. This review discusses recent molecular modeling studies of CCR5 by homology to CXC che- mokine receptor 4, their contribution to the under- standing of the allosteric mode of action of the inhibitor and their potential for the development of future drugs with improved efficiency and preservation of CCR5 biological functions.
Cited literature [26 references]
https://hal-pasteur.archives-ouvertes.fr/pasteur-00743086
Contributor : Cécile Pham <>
Submitted on : Friday, October 18, 2013 - 7:00:05 AM
Last modification on : Friday, October 23, 2020 - 5:01:57 PM
Long-term archiving on: : Friday, March 31, 2017 - 2:38:17 PM
Contributor : Cécile Pham <>
Submitted on : Friday, October 18, 2013 - 7:00:05 AM
Last modification on : Friday, October 23, 2020 - 5:01:57 PM
Long-term archiving on: : Friday, March 31, 2017 - 2:38:17 PM
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