Humanized mice: Current states and perspectives.

Sylvie Garcia (1) , Antonio A Freitas (1)

1 Biologie des Populations Lymphocytaires

The development of chimeric mice bearing the components of a human immune system to serve as animal models for "human" diseases has been the goal of many years of research. In this review we will discuss the latest advances in this field, their remaining shortcomings and challenges to the generation of new models of mouse/human chimeras.

Domains: Immunology

Sylvie Garcia, Antonio A Freitas. Humanized mice: Current states and perspectives.. Immunology Letters, 2012, 146 (1-2), pp.1-7. ⟨10.1016/j.imlet.2012.03.009⟩. ⟨pasteur-00723372⟩