Emergence of IFN-alpha TRAIL-expressing killer pDCs (IKpDCs) as a consequence of a crosstalk with NK cells. Influence of HIV-1 infection and implication of HMGB1

Marlène Bras (1) , Héla Saidi (1) , Pauline Formaglio (1) , Marie-Thérèse Melki (1) , Marie-Lise Gougeon (1)

1 IP - Institut Pasteur [Paris]

Emergence of IFN-alpha TRAIL-expressing killer pDCs (IKpDCs) as a consequence of a crosstalk with NK cells. Influence of HIV-1 infection and implication of HMGB1

Keywords: Plasmacytoid Dendritic Cell; Cell Killing Activity; Antiviral Immunity; Homing Receptor; Maturation Marker

Domains: Life Sciences [q-bio]; Human health and pathology; Infectious diseases

Marlène Bras, Héla Saidi, Pauline Formaglio, Marie-Thérèse Melki, Marie-Lise Gougeon. Emergence of IFN-alpha TRAIL-expressing killer pDCs (IKpDCs) as a consequence of a crosstalk with NK cells. Influence of HIV-1 infection and implication of HMGB1. 17th International Symposium on HIV and Emerging Infectious Diseases (ISHEID), May 2012, Marseille, France. 9 (Suppl 1), pp.P15, 2012, ⟨10.1186/1742-4690-9-S1-P15⟩. ⟨pasteur-00701408⟩