Lymphocyte homeostasis.

Corinne Tanchot (1) , Marie Manuela Rosado (2) , Fabien Agenes (2) , Antonio A. Freitas (2) , Benedita Rocha (1)

1 INEM - UM 111 (UMR 8253 / U1151) - Institut Necker Enfants-Malades
2 Dynamiques Lymphocytaires

B- and T-lymphocyte populations have an independent homeostatic regulation of resting (B and T) and activated (B) or memory (T) cell compartments. This organization may provide an efficient mechanism to ensure simultaneously a first natural barrier of protection against common pathogens, the maintenance of immunological T-cell memory and a reservoir of repertoire diversity capable of dealing with new antigenic challenges.

Domaines: Immunologie

Corinne Tanchot, Marie Manuela Rosado, Fabien Agenes, Antonio A. Freitas, Benedita Rocha. Lymphocyte homeostasis.. Seminars in Immunology, 1997, 9 (6), pp.331-7. ⟨10.1006/smim.1997.0090⟩. ⟨pasteur-00327539⟩