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Journal articles
Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Abstract : Thymidine monophosphate kinase of Mycobacterium tuberculosis (TMPKmt) represents an attractive target for selectively blocking bacterial DNA synthesis. Hereby, we report on the discovery of a novel class of bicyclic nucleosides (10 and 11) and one dinucleoside (12), belonging to the most selective inhibitors of TMPKmt discovered so far.
https://hal-pasteur.archives-ouvertes.fr/pasteur-00166959
Contributor : Hélène Munier-Lehmann Connect in order to contact the contributor
Submitted on : Monday, August 13, 2007 - 4:35:36 PM
Last modification on : Wednesday, November 3, 2021 - 2:56:48 PM
Contributor : Hélène Munier-Lehmann Connect in order to contact the contributor
Submitted on : Monday, August 13, 2007 - 4:35:36 PM
Last modification on : Wednesday, November 3, 2021 - 2:56:48 PM
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