 |
Journal articles
Preparation of synthetic glycoconjugates as potential vaccines against Shigella flexneri serotype 2a disease.
Abstract : The synthesis of three neoglycopeptides incorporating carbohydrate haptens, differing in length, covalently linked to a non natural universal T helper peptide is disclosed. They were synthesized according to a blockwise strategy based on the condensation of appropriate di-, tri-, and tetrasaccharide trichloroacetimidate donors onto an azidoethyl 2-acetamido-2-deoxybeta-D-glucopyranoside acceptor. Use of thiol-maleimide coupling chemistry allowed site-selective efficient conjugation.
https://hal-pasteur.archives-ouvertes.fr/pasteur-00166853
Contributor : Françoise Baleux Connect in order to contact the contributor
Submitted on : Friday, August 10, 2007 - 3:04:55 PM
Last modification on : Tuesday, June 22, 2021 - 10:46:07 AM
Contributor : Françoise Baleux Connect in order to contact the contributor
Submitted on : Friday, August 10, 2007 - 3:04:55 PM
Last modification on : Tuesday, June 22, 2021 - 10:46:07 AM