Carbohydrate antigens: synthesis aspects and immunological applications in cancer.

Teresa Freire (1) , Sylvie Bay (1) , Sophie Vichier-Guerre (1) , Richard Lo-Man (2) , Claude Leclerc (2)

1 Chimie Organique
2 Régulation Immunitaire et Vaccinologie

Tumor Associated Carbohydrate Antigens (TACAs) constitute powerful tools as tumor markers and as targets for anticancer immunotherapy. In this review, methods of production of glycopeptide-based vaccines, as well as results of preclinical and clinical studies in cancer patients are discussed.

Domains: Life Sciences [q-bio]; Microbiology and Parasitology; Life Sciences [q-bio]; Cancer

Teresa Freire, Sylvie Bay, Sophie Vichier-Guerre, Richard Lo-Man, Claude Leclerc. Carbohydrate antigens: synthesis aspects and immunological applications in cancer.. Mini Reviews in Medicinal Chemistry / Mini-Reviews in Medicinal Chemistry, 2006, 6 (12), pp.1357-73. ⟨10.2174/138955706778992996⟩. ⟨pasteur-00166622⟩