Nef–Perkow–Mumm Cascade towards Imido Phosphate Derivatives

Aurélie dos Santos (1) , Marie Cordier (2) , Laurent El Kaim (1)

1 LSO - Laboratoire de Synthèse Organique
2 LCM - Laboratoire de chimie moléculaire

A one-pot, four-component synthesis of imido phosphates has been achieved using a Nef–Perkow sequence followed by addition of carboxylic acid derivatives. The final imido moiety is formed via a Mumm rearrangement of an intermediate imidate.

Domains: Organic chemistry

Aurélie dos Santos, Marie Cordier, Laurent El Kaim. Nef–Perkow–Mumm Cascade towards Imido Phosphate Derivatives. SYNLETT, 2017, 28 (19), pp.2637 - 2641. ⟨10.1055/s-0036-1590856⟩. ⟨hal-01664663⟩