National Monkeypox Surveillance, Central African Republic, 2001–2021 - Archive ouverte HAL Access content directly
Journal Articles Emerging Infectious Diseases Year : 2022

National Monkeypox Surveillance, Central African Republic, 2001–2021

(1, 2) , (3) , (2) , (3) , (3) , (4) , (3) , (3) , (3) , (3) , (5) , (6) , (6) , (1) , (7, 2) , (2) , (2) , (2) , (3)
1
2
3
4
5
6
7
Laura Schaeffer
Jean-Claude Manuguerra
Arnaud Fontanet
  • Function : Correspondent author
  • PersonId : 908680

Connectez-vous pour contacter l'auteur

Abstract

We analyzed monkeypox disease surveillance in Central African Republic (CAR) during 2001-2021. Surveillance data show 95 suspected outbreaks, 40 of which were confirmed as monkeypox, comprising 99 confirmed and 61 suspected monkeypox cases. After 2018, CAR's annual rate of confirmed outbreaks increased, and 65% of outbreaks occurred in 2 forested regions bordering the Democratic Republic of the Congo. The median patient age for confirmed cases was 15.5 years. The overall case-fatality ratio was 7.5% (12/160) for confirmed and suspected cases, 9.6% (8/83) for children <16 years of age. Decreasing cross-protective immunity from smallpox vaccination and recent ecologic alterations likely contribute to increased monkeypox outbreaks in Central Africa. High fatality rates associated with monkeypox virus clade I also are a local and international concern. Ongoing investigations of zoonotic sources and environmental changes that increase human exposure could inform practices to prevent monkeypox expansion into local communities and beyond endemic areas.
Fichier principal
Vignette du fichier
22-0897.pdf (3.49 Mo) Télécharger le fichier
Origin : Publication funded by an institution

Dates and versions

pasteur-03915036 , version 1 (29-12-2022)

Licence

Attribution - CC BY 4.0

Identifiers

Cite

Camille Besombes, Festus Mbrenga, Laura Schaeffer, Christian Malaka, Ella Gonofio, et al.. National Monkeypox Surveillance, Central African Republic, 2001–2021. Emerging Infectious Diseases, 2022, 28 (12), pp.2435-2445. ⟨10.3201/eid2812.220897⟩. ⟨pasteur-03915036⟩
0 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More