The microbiome–nose–brain axis in health and disease

Françoise Lazarini (1) , Emmanuel Roze (2) , Annie Lannuzel (3, 2) , Pierre-Marie Lledo (1)

1 Perception et Mémoire / Perception and Memory
2 ICM - Institut du Cerveau = Paris Brain Institute
3 CIC - Antilles Guyane - Centre d'Investigation Clinique Antilles-Guyane

Growing evidence implicates the bacterial populations in the nose as an important factor for personal and global health. Here, we provide a brief overview of the nasal microbiome and speculate on its potential roles in olfactory processing and neurodegeneration, with a particular focus on Parkinson's disease (PD).

Keywords: Parkinson's disease; microbiota; neuroinflammation; olfaction

Domains: Neurobiology

Françoise Lazarini, Emmanuel Roze, Annie Lannuzel, Pierre-Marie Lledo. The microbiome–nose–brain axis in health and disease. Trends in Neurosciences, In press, ⟨10.1016/j.tins.2022.08.003⟩. ⟨pasteur-03769429⟩