Two-year immunogenicity of a pre-exposure rabies vaccination administered as a two-dose schedule

Laurie Windels (1) , Véronique Naneix-Laroche (2) , Christophe Pasquier (3, 2) , Pierre Delobel (3, 1) , Perrine Parize (4, 5) , Guillaume Martin-Blondel (1, 3)

1 Service des maladies infectieuses et tropicales [Toulouse]
2 CHU Toulouse [Toulouse]
3 Infinity - Institut Toulousain des Maladies Infectieuses et Inflammatoires
4 Lyssavirus, épidémiologie et neuropathologie - Lyssavirus Epidemiology and Neuropathology
5 CNR - Centre National de Référence de la Rage - National Reference Center Rabies

In a young and healthy population, immunogenicity at 2 years of a rabies pre-exposure prophylaxis in a two-dose intramuscular schedule is satisfying. This regimen may be appropriate in people occupationally exposed to RABV, or travelling to highly endemic countries, provided they receive two booster doses in case of exposure.

Domains: Life Sciences [q-bio]

Laurie Windels, Véronique Naneix-Laroche, Christophe Pasquier, Pierre Delobel, Perrine Parize, et al.. Two-year immunogenicity of a pre-exposure rabies vaccination administered as a two-dose schedule. Journal of Travel Medicine, 2022, pp.taac029. ⟨10.1093/jtm/taac029⟩. ⟨pasteur-03696125⟩