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Structure, composition and biological properties of fungal extracellular vesicles

Abstract : ABSTRACT Extracellular vesicles (EVs) are lipidic nanosized particles that deliver a highly complex molecular cargo between cells and organisms and may serve numerous functions in intercellular communication, thereby influencing the evolution of microbial communities. Their roles in infectious diseases have been studied for a long time, comprising viral, bacterial, parasitic and to a less extent, fungal infections. Over the last few years, fungal EVs have become an increasingly active research field. Nevertheless, the understanding of EV functions during fungal infections poses challenging points, comprising the genetics regulating EV release, the EV structural and compositional complexity, the heterogeneity of the EV populations and their impact on host-pathogen interactions. This review explores the state-of-the-art investigations on fungal EVs and how this fast-evolving field can impact the development of new tools to fight fungal infections.
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Contributor : Janbon Guilhem Connect in order to contact the contributor
Submitted on : Thursday, June 9, 2022 - 4:35:28 PM
Last modification on : Tuesday, October 25, 2022 - 3:48:05 PM
Long-term archiving on: : Saturday, September 10, 2022 - 7:37:15 PM


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Distributed under a Creative Commons Attribution 4.0 International License




Juliana Rizzo, Adam Taheraly, Guilhem Janbon. Structure, composition and biological properties of fungal extracellular vesicles. microLife, 2021, 2, pp.uqab009. ⟨10.1093/femsml/uqab009⟩. ⟨pasteur-03692316⟩



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