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Crosstalk between Hepatitis B Virus and the 3D Genome Structure

Abstract : Viruses that transcribe their DNA within the nucleus have to adapt to the existing cellular mechanisms that govern transcriptional regulation. Recent technological breakthroughs have highlighted the highly hierarchical organization of the cellular genome and its role in the regulation of gene expression. This review provides an updated overview on the current knowledge on how the hepatitis B virus interacts with the cellular 3D genome and its consequences on viral and cellular gene expression. We also briefly discuss the strategies developed by other DNA viruses to co-opt and sometimes subvert cellular genome spatial organization.
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Contributor : Romain Koszul Connect in order to contact the contributor
Submitted on : Tuesday, June 7, 2022 - 10:08:19 AM
Last modification on : Thursday, October 13, 2022 - 8:18:43 AM
Long-term archiving on: : Thursday, September 8, 2022 - 6:24:46 PM


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Distributed under a Creative Commons Attribution 4.0 International License




João Diogo Dias, Nazim Sarica, Axel Cournac, Romain Koszul, Christine Neuveut. Crosstalk between Hepatitis B Virus and the 3D Genome Structure. Viruses, 2022, 14 (2), pp.445. ⟨10.3390/v14020445⟩. ⟨pasteur-03689314⟩



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