X-box promoter motif searches: from C. elegans to humans to novel candidate ciliopathies

G Lauter (1) , K Tammimies (1) , A Bieder (1) , R Torchet (1) , H Matsson (1) , M Peyrard (1) , J Burghoorn (1) , E Castren (2) , J Kere (1) , I Tapia-Páez (1) , P Swoboda (1)

1 Karolinska Institutet [Stockholm]
2 Helsingin yliopisto = Helsingfors universitet = University of Helsinki

Ciliary defects are known to cause severe genetic disorders, collectively called ciliopathies. We attempt to identify genes involved in human ciliopathies by making use of the evolutionarily conserved X-box promoter motif recognized by ciliogenic RFX transcription factors.

Domains: Life Sciences [q-bio]; Cellular Biology

G Lauter, K Tammimies, A Bieder, R Torchet, H Matsson, et al.. X-box promoter motif searches: from C. elegans to humans to novel candidate ciliopathies. Cilia, 2015, 4 (S1), pp.P56. ⟨10.1186/2046-2530-4-S1-P56⟩. ⟨pasteur-03681672⟩