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ELIXIR and Toxicology: a community in development

Marvin Martens 1, * Rob Stierum 2 Emma Schymanski 3 Chris Evelo 1, 4 Reza Aalizadeh 5 Hristo Aladjov 6 Kasia Arturi 7 Karine Audouze 8 Pavel Babica 9 Karel Berka 10 Jos Bessems 11 Ludek Blaha 9 Evan Bolton 12 Montserrat Cases 13 Dimitrios Damalas 5 Kirtan Dave 14 Marco Dilger 15 Thomas Exner 16 Daan Geerke 17 Roland Grafström 18, 19 Alasdair Gray 20 John Hancock 21 Henner Hollert 22 Nina Jeliazkova 23 Danyel Jennen 24 Fabien Jourdan 25, 26 Pascal Kahlem Jana Klanova 9 Jos Kleinjans 24 Todor Kondic 3 Boï Kone 27 Iseult Lynch 28 Uko Maran 29 Sergio Martinez Cuesta 30 Hervé Ménager 31, 32 Steffen Neumann 33 Penny Nymark 18 Herbert Oberacher 34 Noelia Ramirez 35 Sylvie Remy 11 Philippe Rocca-Serra 36 Reza Salek 37 Brett Sallach 38 Susanna-Assunta Sansone 36 Ferran Sanz 39 Haralambos Sarimveis 40 Sirarat Sarntivijai 21 Tobias Schulze 41 Jaroslav Slobodnik 42 Ola Spjuth 43 Jonathan Tedds 21 Nikolaos Thomaidis 5 Ralf Weber 28 Gerard van Westen 44 Craig Wheelock 18 Antony Williams 45 Hilda Witters 11 Barbara Zdrazil 46 Anže Županič 47 Egon Willighagen 24, * 
* Corresponding author
Abstract : Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.
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Contributor : Hervé Ménager Connect in order to contact the contributor
Submitted on : Friday, May 27, 2022 - 3:13:28 PM
Last modification on : Friday, November 18, 2022 - 3:20:55 PM
Long-term archiving on: : Tuesday, August 30, 2022 - 10:17:08 AM


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Distributed under a Creative Commons Attribution 4.0 International License



Marvin Martens, Rob Stierum, Emma Schymanski, Chris Evelo, Reza Aalizadeh, et al.. ELIXIR and Toxicology: a community in development. F1000Research, 2021, 10, pp.1129. ⟨10.12688/f1000research.74502.1⟩. ⟨pasteur-03680151⟩



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