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Linking microbiota composition with antimalarial antibody response

Abstract : Microbiota composition recently arose as a factor correlating with malaria infection. Mandal et al. showed, via cecal transplant and antibacterial treatment, that the mouse microbiota modulates parasitemia by affecting spleen germinal centers where B cells are matured. They further identified correlations between microbiota composition and malaria severity in Ugandan children.
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Submitted on : Thursday, May 19, 2022 - 3:06:25 PM
Last modification on : Friday, May 20, 2022 - 3:36:59 AM

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Ottavia Romoli, Liliana Mancio-Silva, Mathilde Gendrin. Linking microbiota composition with antimalarial antibody response. Trends in Parasitology, Elsevier, 2021, 37 (10), pp.853-855. ⟨10.1016/j.pt.2021.07.007⟩. ⟨pasteur-03672692⟩

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