Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei - Archive ouverte HAL Access content directly
Journal Articles mBio Year : 2022

Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei

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Abstract

The single-cell parasite Trypanosoma brucei causes the fatal disease human African trypanosomiasis and is able to colonize the blood, fat, skin, and central nervous system. Trypanosomes survive in the mammalian host owing to a dense protective protein coat that consists of a single-variant surface glycoprotein species.
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pasteur-03647000 , version 1 (20-04-2022)

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Attribution - CC BY 4.0

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Emilia Jane Mclaughlin, Karinna Rubio-Pena, Annick Dujeancourt-Henry, Lucy Glover. Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei. mBio, 2022, 13 (2), pp.e0384721. ⟨10.1128/mbio.03847-21⟩. ⟨pasteur-03647000⟩
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