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Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei

Abstract : The single-cell parasite Trypanosoma brucei causes the fatal disease human African trypanosomiasis and is able to colonize the blood, fat, skin, and central nervous system. Trypanosomes survive in the mammalian host owing to a dense protective protein coat that consists of a single-variant surface glycoprotein species.
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https://hal-pasteur.archives-ouvertes.fr/pasteur-03647000
Contributor : Lucy Glover Connect in order to contact the contributor
Submitted on : Wednesday, April 20, 2022 - 10:35:50 AM
Last modification on : Friday, August 5, 2022 - 12:03:03 PM
Long-term archiving on: : Thursday, July 21, 2022 - 6:21:26 PM

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Emilia Jane Mclaughlin, Karinna Rubio-Pena, Annick Dujeancourt-Henry, Lucy Glover. Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei. mBio, American Society for Microbiology, 2022, 13 (2), pp.e0384721. ⟨10.1128/mbio.03847-21⟩. ⟨pasteur-03647000⟩

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