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Exposures associated with SARS-CoV-2 infection in France: A nationwide online case-control study

Abstract : Background We aimed to assess the role of different setting and activities in acquiring SARS-CoV-2 infection. Methods In this nationwide case-control study, cases were SARS-CoV-2 infected adults recruited between 27 October and 30 November 2020. Controls were individuals from the Ipsos market research database matched to cases by age, sex, region, population density and time period. Participants completed an online questionnaire on recent activity-related exposures. Findings Among 3426 cases and 1713 controls, in multivariable analysis, we found an increased risk of infection associated with any additional person living in the household (adjusted-OR: 1•16; 95%CI: 1•11-1•21); having children attending day-care (aOR: 1•31; 95%CI: 1•02-1•62), kindergarten (aOR: 1•27; 95%CI: 1•09-1•45), middle school (aOR: 1•30; 95%CI: 1•15-1•47), or high school (aOR: 1•18; 95%CI: 1•05-1•34); with attending professional (aOR: 1•15; 95%CI: 1•04-1•26) or private gatherings (aOR: 1•57; 95%CI: 1•45-1•71); and with having frequented bars and restaurants (aOR: 1•95; 95%CI: 1•76-2•15), or having practiced indoor sports activities (aOR: 1•36; 95%CI: 1•15-1•62). We found no increase in risk associated with frequenting shops, cultural or religious gatherings, or with transportation, except for carpooling (aOR: 1•47; 95%CI: 1•28-1•69). Teleworking was associated with decreased risk of infection (aOR: 0•65; 95%CI: 0•56-0•75). Interpretation Places and activities during which infection prevention and control measures may be difficult to fully enforce were those with increased risk of infection. Children attending day-care, kindergarten, middle and high schools, but not primary schools, were potential sources of infection for the household.
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Contributor : Cécile Limouzin Connect in order to contact the contributor
Submitted on : Wednesday, August 25, 2021 - 12:04:27 PM
Last modification on : Wednesday, September 28, 2022 - 5:53:27 AM
Long-term archiving on: : Friday, November 26, 2021 - 7:52:05 PM


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Simon Galmiche, Tiffany Charmet, Laura Schaeffer, Juliette Paireau, Rebecca Grant, et al.. Exposures associated with SARS-CoV-2 infection in France: A nationwide online case-control study. The Lancet Regional Health - Europe, Elsevier, 2021, 7, pp.100148. ⟨10.1016/j.lanepe.2021.100148⟩. ⟨pasteur-03325798⟩



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