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A High-Resolution Microsatellite Map of the Mouse Genome

Abstract : The European Collaborative Interspecific Backcross (EUCIB) resource was constructed for the purposes of high-resolution genetic mapping of the mouse genome (). The large Mus spretus/C57BL/6 backcross of 982 progeny has a genetic resolution of 0.3 cM at the 95% confidence level ( approximately 500 kb in the mouse genome). We have used the EUCIB mapping resource to develop a genome-wide high-resolution genetic map incorporating 3368 microsatellites. The microsatellites are distributed among 2302 genetically separated bins with 1.46 markers per bin on average. Average bin separation is 0.61 cM. This high-resolution genetic map will aid the construction of a robust physical map of the mouse genome.
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Submitted on : Tuesday, June 29, 2021 - 6:06:32 PM
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Michael Rhodes, Richard Straw, Supem Fernando, Andrew Evans, Tregaye Lacey, et al.. A High-Resolution Microsatellite Map of the Mouse Genome. Genome Research, Cold Spring Harbor Laboratory Press, 1998, 8 (5), pp.531-542. ⟨10.1101/gr.8.5.531⟩. ⟨pasteur-03274125⟩



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