Characteristics of Helicobacter pylori strains isolated from Mauritanian patients

Fatimetou Khiddi (1) , Mohamed Val Mohamed Abdellahi (1) , Mohamed Abdallah Horma (2) , Annick Billoet (3) , Ghislaine Collobert (3) , Ahmed Mohamed Amar (2) , Hachem Demine Moctar Nech , El Heiba Mohamed Vadel (4) , Ahmed Houmeida , Josette Raymond (5) , Catherine Dauga (6) , Nabil Gastli (3)

1 Epidemiology and Diversity of Microorganisms [Nouakchott, Mauritania]
2 Chiva Clinic [Nouakchott, Mauritania]
3 Service de Bactériologie [CHU Cochin, AP-HP]
4 Centre Hospitalier National [Nouakchott, Mauritania]
5 AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)
6 Département de Biologie Computationnelle - Department of Computational Biology

Half of the world's population is infected with Helicobacter pylori (H pylori), and approximately 10% to 20% of these individuals will have clinical diseases such as ulcers or gastric cancer (GC). 1 The risk of developing a disease depends not only on host and environmental factors but also virulence factors of H pylori. Different virulence factors, mainly cagA and vacA, may affect the degree and intensity of the individual inflammatory response, which can result in a variety of clinical manifestations in children and adults. 2,3

Keywords: Helicobacter pylori; cagA gene; EPIYA motif; Mauritania; PCR

Domains: Life Sciences [q-bio]; Biodiversity; Systematics, Phylogenetics and taxonomy

Fatimetou Khiddi, Mohamed Val Mohamed Abdellahi, Mohamed Abdallah Horma, Annick Billoet, Ghislaine Collobert, et al.. Characteristics of Helicobacter pylori strains isolated from Mauritanian patients. Helicobacter, 2020, 25, ⟨10.1111/hel.12726⟩. ⟨pasteur-03264978⟩